The Effects of BMP2 on Bone Material and Mineral Characteristics in a Conditional Knockout Mouse Model
نویسنده
چکیده
منابع مشابه
Radioprotective Effects of Sulfur-containing Mineral Water of Ramsar Hot Spring with High Natural Background Radiation on Mouse Bone Marrow Cells
Background: We intend to study the inhibitory effect of sulfur compound in Ramsar hot spring mineral on tumor-genesis ability of high natural background radiation. Objective: The radioprotective effect of sulfur compounds was previously shown on radiation-induced chromosomal aberration, micronuclei in mouse bone marrow cells and human peripheral lymphocyte. Ramsar is known for having the highe...
متن کاملEfficient Simulation of a Random Knockout Tournament
We consider the problem of using simulation to efficiently estimate the win probabilities for participants in a general random knockout tournament. Both of our proposed estimators, one based on the notion of “observed survivals” and the other based on conditional expectation and post-stratification, are highly effective in terms of variance reduction when compared to the raw simulation estimato...
متن کاملLong Bone Structure and Strength Depend on BMP2 from Osteoblasts and Osteocytes, but Not Vascular Endothelial Cells
The importance of bone morphogenetic protein 2 (BMP2) in the skeleton is well known. BMP2 is expressed in a variety of tissues during development, growth and healing. In this study we sought to better identify the role of tissue-specific BMP2 during post-natal growth and to determine if BMP2 knockout affects the ability of terminally differentiated cells to create high quality bone material. We...
متن کاملA GIS-based weights-of-evidence model for mineral potential mapping of hydrothermal gold deposits in Torbat-e-Heydarieh area
The method of weights of evidence is one of the most important data driven methods for mineral potential mapping in GIS. In this method, considering the characteristics of known mineralized locations, we can prospect new mineralized areas. In this research work, the method of weights of evidence has been used for hydrothermal gold potential mapping in Torbat-e-Heydarieh area, east of Iran. As a...
متن کاملBMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development.
The BMP signaling pathway has a crucial role in chondrocyte proliferation and maturation during endochondral bone development. To investigate the specific function of the Bmp2 and Bmp4 genes in growth plate chondrocytes during cartilage development, we generated chondrocyte-specific Bmp2 and Bmp4 conditional knockout (cKO) mice and Bmp2,Bmp4 double knockout (dKO) mice. We found that deletion of...
متن کامل